Bifidobacterium animalis subsp. lactis HN019

Introduction

Microbiology
Profile
  • Gram positive
  • Non spore former
  • Lactic acid production
  • Non-motile facultative anaerobic bacteria or absolute anaerobic bacteria
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    Bifidobacterium animalis subsp. lactis HN019
    Functions
  • Modulation of intestinal flora
  • Improve diarrhea in infants and young children
  • Improve respiratory infections
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    Origin First found in yogurt.
    Genome GenBank

    Functional Studies

    Clinical Trials or Animal Experiments
    ID Category Subject Title Year
    1 clinical trial constipation Effects of 28-day Bifidobacterium animalis subsp. lactis HN019 supplementation on colonic transit time and gastrointestinal symptoms in adults with functional constipation: A double-blind, randomized, placebo-controlled, and dose-ranging trial 2018
    2 clinical trial periodontitis Bifidobacterium animalis subsp lactis HN019 presents antimicrobial potential against periodontopathogens and modulates the immunological response of oral mucosa in periodontitis patients 2020
    3 clinical trial immunity The Effect of Bifidobacterium animalis ssp. lactis HN019 on Cellular Immune Function in Healthy Elderly Subjects: Systematic Review and Meta-Analysis 2017
    4 clinical trial periodontitis Effects of Bifidobacterium probiotic on the treatment of chronic periodontitis: A randomized clinical trial 2018
    5 clinical trial upper respiratory tract infections (URTIs) Comparison of two probiotics in follow-on formula: Bifidobacterium animalis subsp. lactis HN019 reduced upper respiratory tract infections in Chinese infants 2022
    6 clinical trial immunity Enhancement of immunity in the elderly by dietary supplementation with the probiotic Bifidobacterium lactis HN019 2001
    7 clinical trial functional gastrointestinal symptoms Dose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults 2011
    8 clinical trial anemia, iron deficient Effects of Bifidobacterium lactis HN019 and prebiotic oligosaccharide added to milk on iron status, anemia, and growth among children 1 to 4 years old 2010
    9 clinical trial modulate gut microbiota Impact of consumption of different levels of Bifidobacterium lactis HN019 on the intestinal microflora of elderly human subjects 2007
    10 clinical trial immunity Enhancement of natural immune function by dietary consumption of Bifidobacterium lactis (HN019) 2000
    11 clinical trial constipation Effect of yogurt containing polydextrose, Lactobacillus acidophilus NCFM and Bifidobacterium lactis HN019: a randomized, double-blind, controlled study in chronic constipation 2014
    12 clinical trial modulate gut microbiota Effects of Bifidobacterium animalis lactis HN019 (DR10TM), inulin, and micronutrient fortified milk on faecal DR10TM, immune markers, and maternal micronutrients among Indonesian pregnant women 2016
    13 clinical trial functional gastrointestinal symptoms The effect of a probiotic blend on gastrointestinal symptoms in constipated patients: a double blind, randomised, placebo controlled 2-week trial 2019
    14 clinical trial immunity Enhancing immunity by dietary consumption of a probiotic lactic acid bacterium (Bifidobacterium lactis HN019): optimization and definition of cellular immune responses 2000
    15 clinical trial peri-implant mucositis (PiM) Adjuvant use of multispecies probiotic in the treatment of peri-implant mucositis: A randomized controlled trial 2022
    16 clinical trial eczema Differential effects of two probiotics on the risks of eczema and atopy associated with single nucleotide polymorphisms to Toll-like receptors 2015
    17 clinical trial allergic disease Effects of Lactobacillus rhamnosus HN001 in early life on the cumulative prevalence of allergic disease to 11 years 2018
    18 clinical trial constipation Contemporary meta-analysis of short-term probiotic consumption on gastrointestinal transit 2016
    19 clinical trial eczema Differential modification of genetic susceptibility to childhood eczema by two probiotics 2014
    20 clinical trial eczema A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years 2012
    21 animal experiment immunity Enhancement of natural and acquired immunity by Lactobacillus rhamnosus (HN001), Lactobacillus acidophilus (HN017) and Bifidobacterium lactis (HN019) 2000
    22 animal experiment immunity Immunostimulatory probiotic Lactobacillus rhamnosus HN001 and Bifidobacterium lactis HN019 do not induce pathological inflammation in mouse model of experimental autoimmune thyroiditis 2005
    23 animal experiment immunity A dietary probiotic (Bifidobacterium lactis HN019) reduces the severity of Escherichia coli O157:H7 infection in mice 2001
    24 animal experiment immunity Fermented or unfermented milk using Bifidobacterium animalis subsp. lactis HN019: Technological approach determines the probiotic modulation of mucosal cellular immunity 2014
    25 animal experiment diarrhea Probiotic treatment using Bifidobacterium lactis HN019 reduces weanling diarrhea associated with rotavirus and Escherichia coli infection in a piglet model 2001
    26 animal experiment immunity Dietary Bifidobacterium lactis (HN019) enhances resistance to oral Salmonella typhimurium infection in mice 2000

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