MAMI

Bifidobacterium animalis subsp. lactis Bi-07

Introduction

Microbiology Profile	Gram positive Non spore former Lactic acid production Non-motile anaerobic bacteria	Bifidobacterium animalis subsp. lactis Bi-07
Functions	Modulation of intestinal flora Strengthen immunity Improve eczema in infants and young children	Bifidobacterium animalis subsp. lactis Bi-07
Origin	First found in human gut.
Genome	GenBank

Functional Studies

Clinical Trials or Animal Experiments
ID	Category	Subject	Title	Year
1	clinical trial	functional bowel disorders (FBDs)	Probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 versus placebo for the symptoms of bloating in patients with functional bowel disorders: a double-blind study	2011
2	clinical trial	C. difficile infection (CDI)	A randomized controlled trial of probiotics for Clostridium difficile infection in adults (PICO)	2017
3	clinical trial	modulate gut microbiota	Do Probiotics During In-Hospital Antibiotic Treatment Prevent Colonization of Gut Microbiota With Multi-Drug-Resistant Bacteria? A Randomized Placebo-Controlled Trial Comparing Saccharomyces to a Mixture of Lactobacillus, Bifidobacterium, and Saccharomyces	2021
4	clinical trial	upper respiratory infection (URI)	Ex vivo peripheral blood mononuclear cell response to R848 in children after supplementation with the probiotic Lactobacillus acidophilus NCFM/ Bifidobacterium lactis Bi-07	2021
5	clinical trial	insulin sensitivity and the systemic inflammatory	Effects of Lactobacillus acidophilus NCFM on insulin sensitivity and the systemic inflammatory response in human subjects	2010
6	clinical trial	functional gastrointestinal symptoms	The effect of a probiotic blend on gastrointestinal symptoms in constipated patients: a double blind, randomised, placebo controlled 2-week trial	2019
7	clinical trial	constipation	Effect of the consumption of a cheese enriched with probiotic organisms (Bifidobacterium lactis bi-07) in improving symptoms of constipation	2013
8	clinical trial	atopic dermatitis (AD)	Predominant genera of fecal microbiota in children with atopic dermatitis are not altered by intake of probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium animalis subsp. lactis Bi-07	2011
9	clinical trial	upper respiratory infection (URI), gastrointestinal illness	Probiotic supplementation for respiratory and gastrointestinal illness symptoms in healthy physically active individuals	2014
10	clinical trial	immunity	Xylo-oligosaccharides alone or in synbiotic combination with Bifidobacterium animalis subsp. lactis induce bifidogenesis and modulate markers of immune function in healthy adults: a double-blind, placebo-controlled, randomised, factorial cross-over study	2014
11	clinical trial	modulate gut microbiota	Randomized controlled trial of probiotics after colonoscopy	2017
12	clinical trial	inflammation	Potential Modulation of Inflammation by Probiotic and Omega-3 Supplementation in Elderly with Chronic Low-Grade Inflammation-A Randomized, Placebo-Controlled Trial	2022
13	clinical trial	metabolic health	Effect of probiotic supplementation on plasma metabolite profile after Roux-Y gastric bypass: a prospective, randomized, double-blind, placebo-controlled clinical trial	2022
14	clinical trial, animal experiment	modulate gut microbiota, immunity	Fermented milk supplemented with probiotics and prebiotics can effectively alter the intestinal microbiota and immunity of host animals	2012
15	clinical trial	influenza	Probiotic effects on cold and influenza-like symptom incidence and duration in children	2009
16	clinical trial	acute diarrhoea	A combination of three probiotic strains for treatment of acute diarrhoea in hospitalised children: an open label, randomised controlled trial	2020
17	animal experiment	antibiotic-associated diarrhea (AAD)	New compound probiotic beverage protects against antibiotic-associated diarrhea in mice by modulating the microbiota	2022

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