Bifidobacterium longum subsp. longum BB536

Introduction

Microbiology
Profile
  • Gram positive
  • Rod shape
  • Anaerobic bacteria
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    Bifidobacterium longum. infantis BB536
    Functions
  • Modulation of intestinal microbiota
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    Origin First found in infant gut.
    Genome

    Functional Studies

    Clinical Trials or Animal Experiments
    ID Category Subject Title Year
    1 clinical trial modulate gut microbiota Effect of Lactobacillus rhamnosus HN001 and Bifidobacterium longum BB536 on the healthy gut microbiota composition at phyla and species level: A preliminary study 2017
    2 clinical trial cardiovascular risk Nutraceutical approach for the management of cardiovascular risk - a combination containing the probiotic Bifidobacterium longum BB536 and red yeast rice extract: results from a randomized, double-blind, placebo-controlled study 2019
    3 clinical trial irritable bowel syndrome (IBS) Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients 2020
    4 clinical trial functional gastrointestinal symptoms Effects of Bifidobacterium longum and Lactobacillus rhamnosus on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study 2019
    5 clinical trial upper respiratory tract infections (URTIs) Bifidobacterium longum BB536 alleviated upper respiratory illnesses and modulated gut microbiota profiles in Malaysian pre-school children 2018
    6 clinical trial defecation Modulatory effects of Bifidobacterium longum BB536 on defecation in elderly patients receiving enteral feeding 2013
    7 clinical trial immunity Clinical effects of probiotic Bifidobacterium longum BB536 on immune function and intestinal microbiota in elderly patients receiving enteral tube feeding 2013
    8 clinical trial influenza infection Effects of Bifidobacterium longum BB536 administration on influenza infection, influenza vaccine antibody titer, and cell-mediated immunity in the elderly 2010
    9 clinical trial allergy Effect of probiotic Bifidobacterium longum BB536 [corrected] in relieving clinical symptoms and modulating plasma cytokine levels of Japanese cedar pollinosis during the pollen season. A randomized double-blind, placebo-controlled trial 2006
    10 clinical trial cardiovascular risk Interactions of Oxysterols with Atherosclerosis Biomarkers in Subjects with Moderate Hypercholesterolemia and Effects of a Nutraceutical Combination ( Bifidobacterium longum BB536, Red Yeast Rice Extract) (Randomized, Double-Blind, Placebo-Controlled Study) 2021
    11 clinical trial immunity Modulation of T Regulatory and Dendritic Cell Phenotypes Following Ingestion of Bifidobacterium longum, AHCC® and Azithromycin in Healthy Individuals 2019
    12 clinical trial allergy Probiotics in the treatment of Japanese cedar pollinosis: a double-blind placebo-controlled trial 2006
    13 clinical trial ulcerative colitis Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial 2016
    14 clinical trial allergic rhinitis (AR), allergic asthma Bifidobacterium mixture (B longum BB536, B infantis M-63, B breve M-16V) treatment in children with seasonal allergic rhinitis and intermittent asthma 2017
    15 clinical trial breast cancer (BC) Gut microbiota composition after diet and probiotics in overweight breast cancer survivors: a randomized open-label pilot intervention trial 2020
    16 clinical trial allergy Clinical efficacy of probiotic Bifidobacterium longum for the treatment of symptoms of Japanese cedar pollen allergy in subjects evaluated in an environmental exposure unit 2007
    17 clinical trial immunity, modulate gut microbiota Effects of Bifidobacterium supplementation on intestinal microbiota composition and the immune response in healthy infants 2016
    18 animal experiment modulate gut microbiota Probiotic Bifidobacterium longum alters gut luminal metabolism through modification of the gut microbial community 2015
    19 animal experiment influenza virus infection Oral administration of Bifidobacterium longum ameliorates influenza virus infection in mice 2011
    20 animal experiment allergy In vitro Th1 cytokine-independent Th2 suppressive effects of bifidobacteria 2007
    21 animal experiment schizophrenia Effect of repeated oral administration of Bifidobacterium longum BB536 on apomorphine-induced rearing behavior in mice 2016
    22 animal experiment gut-derived sepsis Oral administration of Bifidobacterium longum prevents gut-derived Pseudomonas aeruginosa sepsis in mice 2008

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