Lactobacillus acidophilus NCFM

Introduction

Microbiology
Profile
  • Gram positive
  • Rod shape
  • Release lactic acid, acetic acid
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    Lactobacillus acidophilus NCFM
    Functions
  • Improve atopic dermatitis
  • Improve diarrhea
  • Immunoregulation
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    Origin First found in human gut.
    Genome NCBI

    Functional Studies

    Clinical Trials or Animal Experiments
    ID Category Subject Title Year
    1 clinical trial functional bowel disorders (FBDs) Probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 versus placebo for the symptoms of bloating in patients with functional bowel disorders: a double-blind study 2011
    2 clinical trial irritable bowel syndrome (IBS) Irritable bowel syndrome symptom severity improves equally with probiotic and placebo 2016
    3 clinical trial abdominal pain Lactobacillus acidophilus NCFM affects colonic mucosal opioid receptor expression in patients with functional abdominal pain - a randomised clinical study 2014
    4 clinical trial C. difficile infection (CDI) A randomized controlled trial of probiotics for Clostridium difficile infection in adults (PICO) 2017
    5 clinical trial modulate gut microbiota Do Probiotics During In-Hospital Antibiotic Treatment Prevent Colonization of Gut Microbiota With Multi-Drug-Resistant Bacteria? A Randomized Placebo-Controlled Trial Comparing Saccharomyces to a Mixture of Lactobacillus, Bifidobacterium, and Saccharomyces 2021
    6 clinical trial insulin sensitivity and the systemic inflammatory Effects of Lactobacillus acidophilus NCFM on insulin sensitivity and the systemic inflammatory response in human subjects 2010
    7 clinical trial upper respiratory infection (URI) Ex vivo peripheral blood mononuclear cell response to R848 in children after supplementation with the probiotic Lactobacillus acidophilus NCFM/ Bifidobacterium lactis Bi-07 2021
    8 clinical trial modulate gut microbiota Synbiotic Lactobacillus acidophilus NCFM and cellobiose does not affect human gut bacterial diversity but increases abundance of lactobacilli, bifidobacteria and branched-chain fatty acids: a randomized, double-blinded cross-over trial 2014
    9 clinical trial modulate gut microbiota Probiotic cheese containing Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus NCFM® modifies subpopulations of fecal lactobacilli and Clostridium difficile in the elderly 2012
    10 clinical trial modulate gut microbiota Influence of a combination of Lactobacillus acidophilus NCFM and lactitol on healthy elderly: intestinal and immune parameters 2009
    11 clinical trial atopic dermatitis (AD) Predominant genera of fecal microbiota in children with atopic dermatitis are not altered by intake of probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium animalis subsp. lactis Bi-07 2011
    12 clinical trial constipation Effect of yogurt containing polydextrose, Lactobacillus acidophilus NCFM and Bifidobacterium lactis HN019: a randomized, double-blind, controlled study in chronic constipation 2014
    13 clinical trial modulate gut microbiota Gut microbiota of healthy elderly NSAID users is selectively modified with the administration of Lactobacillus acidophilus NCFM and lactitol 2012
    14 clinical trial constipation The effect of a probiotic blend on gastrointestinal symptoms in constipated patients: a double blind, randomised, placebo controlled 2-week trial 2019
    15 clinical trial irritable bowel syndrome (IBS) Lactobacillus acidophilus versus placebo in the symptomatic treatment of irritable bowel syndrome: the LAPIBSS randomized trial 2017
    16 clinical trial oral candidiasis Cheese supplemented with probiotics reduced the Candida levels in denture wearers-RCT 2017
    17 clinical trial metabolic health Effect of probiotic supplementation on plasma metabolite profile after Roux-Y gastric bypass: a prospective, randomized, double-blind, placebo-controlled clinical trial 2022
    18 clinical trial upper respiratory infection (URI), gastrointestinal illness Probiotic supplementation for respiratory and gastrointestinal illness symptoms in healthy physically active individuals 2014
    19 clinical trial modulate gut microbiota Randomized controlled trial of probiotics after colonoscopy 2017
    20 clinical trial Inflammatory non-allergic rhinitis (INAR) Adjuvant treatment with a symbiotic in patients with inflammatory non-allergic rhinitis 2017
    21 clinical trial allergic rhinitis Specific probiotics alleviate allergic rhinitis during the birch pollen season 2009
    22 clinical trial acute diarrhoea A combination of three probiotic strains for treatment of acute diarrhoea in hospitalised children: an open label, randomised controlled trial 2020
    23 clinical trial, animal experiment modulate gut microbiota, immunity Fermented milk supplemented with probiotics and prebiotics can effectively alter the intestinal microbiota and immunity of host animals 2012
    24 clinical trial influenza Probiotic effects on cold and influenza-like symptom incidence and duration in children 2009
    25 animal experiment metabolic health Lactobacillus acidophilus NCFM affects vitamin E acetate metabolism and intestinal bile acid signature in monocolonized mice 2014
    26 clinical trial, animal experiment abdominal pain Lactobacillus acidophilus NCFM affects colonic mucosal opioid receptor expression in patients with functional abdominal pain - a randomised clinical study 2014
    27 animal experiment antibiotic-associated diarrhea (AAD) New compound probiotic beverage protects against antibiotic-associated diarrhea in mice by modulating the microbiota 2022

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